Draft White Paper: Modifying EPA Radiation Risk...BEIR VII, by ORIA, EPA, 8/1/2006

Draft White Paper: Modifying EPA Radiation Risk Models Based on BEIR VII

Epa 402-r-93-076 Estimating Radiogenic Cancer Risks

ii The scientific basis for this report has been reviewed formally by the Radiation Advisory Committee (RAC) of the EPA Science Advisory Board (SAB). The following paragraph is a synopsis of that review. (now the Office of Radiation and Indoor Air or ORIA) requested that the RAC review an issues paper comparing health risk estimates due to low level exposures of low-LET radiation based on model...

Cancer Risk Assessment due to Accidental Exposure inside Neutron Laboratories using BEIR VII Model

Introduction: Environmental and occupational human exposure from neutron source can lead to the serious biologic effects. The aim of this study is to evaluate the cancer incidence risk for various human organs at different neutron dose levels due to exposure from an Americium-241/Beryllium (Am-241/Be), a standard neutron source for calibration purposes. Material and Methods: We measured ambient...

Effects of low level radiation-what's new?

A comprehensive review of the effects of exposure to low levels of ionizing radiation, BEIR VII-Phase 2: Health Risks From Exposure to Low Levels of Ionizing Radiation, was published in 2006. The BEIR (Biological Effects of Ionizing Radiation) reports are a series of publications by the National Academy of Sciences. The last BEIR report on the effects of low level radiation, BEIR V, was publish...

The role of dose rate in radiation cancer risk: evaluating the effect of dose rate at the molecular, cellular and tissue levels using key events in critical pathways following exposure to low LET radiation

PURPOSE This review evaluates the role of dose rate on cell and molecular responses. It focuses on the influence of dose rate on key events in critical pathways in the development of cancer. This approach is similar to that used by the U.S. EPA and others to evaluate risk from chemicals. It provides a mechanistic method to account for the influence of the dose rate from low-LET radiation, espec...